David, I have always heard it pronounced, as you pronounce it, "Kah-nee-sus". I would suppose that folks from the Buffalo area would be more inclined to say it with the "yus" sound, simply because they're more familiar with that name. I would also have to assume, that there is a likelihood of a "Cansius" presence in areas other than Buffalo, but I'll bet you mostly heard it from Buffalo people. OR...they probably the same people who say "NUK-U-LAR!! Go figure!! Carole